Structure of PDB 2ivo Chain A

Receptor sequence
>2ivoA (length=325) Species: 29292 (Pyrococcus abyssi) [Search protein sequence]
MLALGIEGTAHTLGIGIVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARL
MKPLLRKALSEAGVSLDDIDVIAFSQGPGLGPALRVVATAARALAVKYRK
PIVGVNHCIAHVEITKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETL
DIGIGNAIDVFARELGLGFPGGPKVEKLAEKGEKYIELPYAVKGMDLSFS
GLLTEAIRKYRSGKYRVEDLAYSFQETAFAALVEVTERAVAHTEKDEVVL
VGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYKA
GISFRLEETIVKQKFRTDEVEIVWH
3D structure
PDB2ivo An Archaeal Orthologue of the Universal Protein Kae1 is an Iron Metalloprotein which Exhibits Atypical DNA-Binding Properties and Apurinic-Endonuclease Activity in Vitro.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WO4 A P82 R85 Q313 P82 R85 Q313
BS02 WO4 A R85 R92 I310 V311 R85 R92 I310 V311
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003727 single-stranded RNA binding
GO:0005506 iron ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process
Cellular Component
GO:0000408 EKC/KEOPS complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ivo, PDBe:2ivo, PDBj:2ivo
PDBsum2ivo
PubMed17766251
UniProtQ9UXT7|KAE1_PYRAB tRNA N6-adenosine threonylcarbamoyltransferase (Gene Name=kae1)

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