Structure of PDB 2iui Chain A

Receptor sequence
>2iuiA (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MSLQNAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKG
GNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLL
YPVSKYQ
3D structure
PDB2iui Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R19 R37 S40 T48 L59 I60 K61 S72 D73 P74 Y95 N96 L99 R15 R33 S36 T44 L55 I56 K57 S68 D69 P70 Y91 N92 L95
External links
PDB RCSB:2iui, PDBe:2iui, PDBj:2iui
PDBsum2iui
PubMed8599763
UniProtP27986|P85A_HUMAN Phosphatidylinositol 3-kinase regulatory subunit alpha (Gene Name=PIK3R1)

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