Structure of PDB 2iry Chain A

Receptor sequence
>2iryA (length=288) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
GSASEQRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATR
KRWPNGVDQPAFFEKQLALSAPPWLSRATVAHRSGTTTYPIIDSATGLAW
IAQQAALEVHVPQWRFVAEPGSGELNPGPATRLVFDLDPGEGVMMAQLAE
VARAVRDLLADIGLVTFPVTSGSKGLHLYTPLDEPVSSRGATVLAKRVAQ
RLEQAMPALVTSTMTKSLRAGKVFVDWSQNSGSKTTIAPYSLRGRTHPTV
AAPRTWAELDDPALRQLSYDEVLTRIARDGDLLERLDA
3D structure
PDB2iry Structure and function of a mycobacterial NHEJ DNA repair polymerase.
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.1: DNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D140 D142 D136 D138
BS02 DGT A F67 K69 D140 S175 S177 K178 G179 H181 T239 R247 F63 K65 D136 S171 S173 K174 G175 H177 T235 R243
External links
PDB RCSB:2iry, PDBe:2iry, PDBj:2iry
PDBsum2iry
PubMed17174332
UniProtP9WNV3|LIGD_MYCTU Multifunctional non-homologous end joining DNA repair protein LigD (Gene Name=ligD)

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