Structure of PDB 2iq1 Chain A

Receptor sequence
>2iq1A (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
ISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCH
THMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLATLLTSGTTATV
ALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGG
FVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSF
LVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAV
VVPFGAW
3D structure
PDB2iq1 Structural genomics of protein phosphatases
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
3.1.3.52: [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]- phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D127 G128 D38 G39
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2iq1, PDBe:2iq1, PDBj:2iq1
PDBsum2iq1
PubMed18058037
UniProtQ8N3J5|PPM1K_HUMAN Protein phosphatase Mn(2+)-dependent 1K (Gene Name=PPM1K)

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