Structure of PDB 2ipx Chain A

Receptor sequence
>2ipxA (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]
MVEPHRHEGVFICRLVTKNLVPGESVYGEKRVSISKIEYRAWNPFRSKLA
AAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR
SGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRI
VALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQE
QLTLEPYERDHAVVVGVYRP
3D structure
PDB2ipx The Crystal Structure of Human Fibrillarin in complex with SAH
ChainA
Resolution1.82 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MTA A G168 A170 E192 F193 D217 A218 V238 Q240 G72 A74 E96 F97 D121 A122 V142 Q144
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
Biological Process
GO:0006364 rRNA processing

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2ipx, PDBe:2ipx, PDBj:2ipx
PDBsum2ipx
PubMed
UniProtP22087|FBRL_HUMAN rRNA 2'-O-methyltransferase fibrillarin (Gene Name=FBL)

[Back to BioLiP]