Structure of PDB 2ioi Chain A

Receptor sequence
>2ioiA (length=187) Species: 10090 (Mus musculus) [Search protein sequence]
QKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSA
TPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEG
NLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRR
PILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEE
3D structure
PDB2ioi High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1173 H1176 C1235 C1239 C77 H80 C139 C143
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ioi, PDBe:2ioi, PDBj:2ioi
PDBsum2ioi
PubMed17139084
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

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