Structure of PDB 2ifc Chain A

Receptor sequence
>2ifcA (length=380) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
EEISKGLEDVNIKWTRLTTIDGNKGILRYGGYSVEDIIASGAQDEEIQYL
FLYGNLPTEQELRKYKETVQKGYKIPDFVINAIRQLPRESDAVAMQMAAV
AAMAASETKFKWNKDTDRDVAAEMIGRMSAITVNVYRHIMNMPAELPKPS
DSYAESFLNAAFGRKATKEEIDAMNTALILYTDHEVPASTTAGLVAVSTL
SDMYSGITAALAALKGPLHGGAAEAAIAQFDEIKDPAMVEKWFNDNIING
KKRLMGFGHRVYKTYDPRAKIFKGIAEKLSSKKPEVHKVYEIATKLEDFG
IKAFGSKGIYPNTDYFSGIVYMSIGFPLRNNIYTALFALSRVTGWQAHFI
EYVEEQQRLIRPRAVYVGPAERKYVPIAER
3D structure
PDB2ifc To be anounced
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S192 H222 H262 R271 D317
Catalytic site (residue number reindexed from 1) S189 H219 H259 R268 D314
Enzyme Commision number 2.3.3.16: citrate synthase (unknown stereospecificity).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OAA A H187 P190 H262 R271 R344 H184 P187 H259 R268 R341
Gene Ontology
Molecular Function
GO:0004108 citrate (Si)-synthase activity
GO:0016740 transferase activity
GO:0036440 citrate synthase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ifc, PDBe:2ifc, PDBj:2ifc
PDBsum2ifc
PubMed
UniProtP21553|CISY_THEAC Citrate synthase (Gene Name=gltA)

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