Structure of PDB 2id0 Chain A

Receptor sequence
>2id0A (length=636) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
NPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKV
MHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPDHP
LLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFG
DDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSAS
TEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYL
PGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAAT
IESKAKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNH
ALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVL
RDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRR
ELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGD
MINHRLLKAVIKGRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKA
GTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENG
TVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPVA
3D structure
PDB2id0 Structural Basis for Processivity and Single-Strand Specificity of RNase II.
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D201 D207 D209 D210 Y313 R500
Catalytic site (residue number reindexed from 1) D197 D203 D205 D206 Y309 R496
Enzyme Commision number 3.1.13.1: exoribonuclease II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D201 D210 D197 D206
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004527 exonuclease activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0008859 exoribonuclease II activity
Biological Process
GO:0006401 RNA catabolic process
GO:0006402 mRNA catabolic process
GO:0016070 RNA metabolic process
GO:0016078 tRNA decay
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2id0, PDBe:2id0, PDBj:2id0
PDBsum2id0
PubMed16996291
UniProtP30850|RNB_ECOLI Exoribonuclease 2 (Gene Name=rnb)

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