Structure of PDB 2ics Chain A

Receptor sequence
>2icsA (length=368) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
DYDLLIKNGQTVNGMPVEIAIKEKKIAAVAATISGSAKETIHLEPGTYVS
AGWIDDHVHCFEKMALYYDYPDEIGVKKGVTTVIDAGTTGAENIHEFYDL
AQQAKTNVFGLVNISKWGIVAQDELADLSKVQASLVKKAIQELPDFVVGI
KARMSRTVIGDNGITPLELAKQIQQENQEIPLMVHIGSAPPHLDEILALM
EKGDVLTHCFNGKENGILDQATDKIKDFAWQAYNKGVVFDIGHGTDSFNF
HVAETALREGMKAASISTDIYIRNRENGPVYDLATTMEKLRVVGYDWPEI
IEKVTKAPAENFHLTQKGTLEIGKDADLTIFTIQAEEKTLTDSNGLTRVA
KEQIRPIKTIIGGQIYDN
3D structure
PDB2ics Crystal structure of an adenine deaminase
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H60 H62 K154 D272 H57 H59 K151 D269
BS02 ZN A K154 H188 H211 K151 H185 H208
BS03 ADE A Y70 Q125 R156 H188 Y67 Q122 R153 H185
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0019213 deacetylase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2ics, PDBe:2ics, PDBj:2ics
PDBsum2ics
PubMed
UniProtQ837K0|DEACT_ENTFA Deacetylase EF_0837 (Gene Name=EF_0837)

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