Structure of PDB 2ibn Chain A

Receptor sequence
>2ibnA (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
SMDRVFTTYKLMHTHQTVDFVRSKHAQFGGFSYKKMTVMEAVDLLDGLVD
ESDDFPNSFHAFQTAEGIRKAHPDKDWFHLVGLLHDLGKVLALFGEPQWA
VVGDTFPVGCRPQASVVFCDSTFQDNPDLQDPRYSTELGMYQPHCGLDRV
LMSWGHDEYMYQVMKFNKFSLPPEAFYMIRFHSFYPWHTGRDYQQLCSQQ
DLAMLPWVREFNKFDLLPDVDKLRPYYQGLIDKYCPGILSW
3D structure
PDB2ibn Structural and Biophysical Characterization of Human myo-Inositol Oxygenase
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.13.99.1: inositol oxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H98 H123 D124 D253 H60 H85 D86 D215
BS02 FE A D124 H194 H220 D86 H156 H182
BS03 I1N A D85 S87 D124 K127 G141 D142 H194 H220 S221 D50 S52 D86 K89 G103 D104 H156 H182 S183
BS04 CYS A W225 R229 Q232 C235 L240 W187 R191 Q194 C197 L202
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0050113 inositol oxygenase activity
Biological Process
GO:0019310 inositol catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2ibn, PDBe:2ibn, PDBj:2ibn
PDBsum2ibn
PubMed18364358
UniProtQ9UGB7|MIOX_HUMAN Inositol oxygenase (Gene Name=MIOX)

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