Structure of PDB 2i82 Chain A

Receptor sequence
>2i82A (length=217) Species: 562 (Escherichia coli) [Search protein sequence]
MENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQR
DYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARV
VLKPITGRSHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTI
THPAYGNSMTFKAPADF
3D structure
PDB2i82 Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.99.28: tRNA pseudouridine(32) synthase.
5.4.99.29: 23S rRNA pseudouridine(746) synthase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
GO:0106029 tRNA pseudouridine synthase activity
GO:0120159 rRNA pseudouridine synthase activity
GO:0140098 catalytic activity, acting on RNA
GO:0160142 23S rRNA pseudouridine(746) synthase activity
GO:0160151 tRNA pseudouridine(32) synthase activity
Biological Process
GO:0000455 enzyme-directed rRNA pseudouridine synthesis
GO:0001522 pseudouridine synthesis
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0008033 tRNA processing
GO:0009451 RNA modification
GO:0031118 rRNA pseudouridine synthesis
GO:0031119 tRNA pseudouridine synthesis

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Molecular Function

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Biological Process
External links
PDB RCSB:2i82, PDBe:2i82, PDBj:2i82
PDBsum2i82
PubMed17188032
UniProtP0AA37|RLUA_ECOLI Dual-specificity RNA pseudouridine synthase RluA (Gene Name=rluA)

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