Structure of PDB 2i55 Chain A

Receptor sequence
>2i55A (length=242) Species: 5665 (Leishmania mexicana) [Search protein sequence]
KAILLFDVDGTLTPPRNPETHDMKEALLKARAAGFKLGVVGGSDFAKQKE
QLGESILEDFDYVFSENGLLAYKDGKEFHRNSLLRALGNEKVVAFVKKCL
HLIADLDIPVQRGTFVEFRNGMFNVSPIGRNCSQQERDEFENLDKERHIR
EKLIRELKEAFPDYQLAYSVGGQISFDVFPKGWDKTYCLQFVENDFETIH
FFGDKTSEGGNDYEIFTDSRTIGHSVKTYKDTIAILEALLED
3D structure
PDB2i55 Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.2.8: phosphomannomutase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D10 D207 D7 D204
Gene Ontology
Molecular Function
GO:0004615 phosphomannomutase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006013 mannose metabolic process
GO:0006487 protein N-linked glycosylation
GO:0009298 GDP-mannose biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2i55, PDBe:2i55, PDBj:2i55
PDBsum2i55
PubMed16963079
UniProtQ95ZD7

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