Structure of PDB 2i13 Chain A

Receptor sequence

>2i13A (length=151) Species: 10090 (Mus musculus) [Search protein sequence]

FSRSDHLAEHQRTHKPYKCPECGKSFSDKKDLTRHQRTHTGEKPYKCPEC
GKSFSQRANLRAHQRTHTGEKPYACPECGKSFSQLAHLRAHQRTHTGEKP
YKCPECGKSFSREDNLHTHQRTHTGEKPYKCPECGKSFSRRDALNVHQRT
H

3D structure

PDB

2i13 Structure of Aart, a Designed Six-finger Zinc Finger Peptide, Bound to DNA.

Chain

Resolution

1.96 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	R33 H36 F59 D64 R67 H68 T71 K85 F87 Q89 N92 H96 T99 Q117 H120 H124 F143 R145 N148 H152 T155 F171 R173 H180 T183	R3 H6 F26 D31 R34 H35 T38 K52 F54 Q56 N59 H63 T66 Q84 H87 H91 F110 R112 N115 H119 T122 F138 R140 H147 T150
BS02	dna	A	D35 K63 R90 D147 H150 D175	D5 K30 R57 D114 H117 D142
BS03	GOL	A	H120 R145	H87 R112
BS04	ZN	A	H40 H44	H10 H14
BS05	ZN	A	C80 C83 H96 H100	C47 C50 H63 H67
BS06	ZN	A	C108 C111 H124 H128	C75 C78 H91 H95
BS07	ZN	A	C136 C139 H152 H156	C103 C106 H119 H123
BS08	ZN	A	C164 C167 H180 H184	C131 C134 H147 H151
BS09	ZN	A	C52 C55 H68 H72	C19 C22 H35 H39

External links

PDB	RCSB:2i13, PDBe:2i13, PDBj:2i13
PDBsum	2i13
PubMed	16963084
UniProt	Q07230\|ZSCA2_MOUSE Zinc finger and SCAN domain-containing protein 2 (Gene Name=Zscan2)

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