Structure of PDB 2i06 Chain A

Receptor sequence

>2i06A (length=305) Species: 562 (Escherichia coli) [Search protein sequence]

DLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEVKKEDEHNPLN
RIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVDN
LSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLN
AYRTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWT
REEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHA
CPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLH
LYVAD

3D structure

PDB

2i06 A molecular mousetrap determines polarity of termination of DNA replication in E. coli

Chain

Resolution

2.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	S88 K89 T129 F140 H144 G149 Y156 R169 A173 N174 K175 H176 I178 K179 N180 K229 R241 W243 Q250 V285 Q286 H287 R288 P291 A293	S84 K85 T125 F136 H140 G145 Y152 R165 A169 N170 K171 H172 I174 K175 N176 K225 R237 W239 Q246 V281 Q282 H283 R284 P287 A289
BS02	dna	A	H50 K89 A90 A91 R93 L153 R157 T158 K175 R198 R232 V234 K235 Q252 Y289 R302	H46 K85 A86 A87 R89 L149 R153 T154 K171 R194 R228 V230 K231 Q248 Y285 R298

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding

	Biological Process
GO:0006260	DNA replication
GO:0006274	DNA replication termination
GO:0071807	replication fork arrest involved in DNA replication termination

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:2i06, PDBe:2i06, PDBj:2i06
PDBsum	2i06
PubMed
UniProt	P16525\|TUS_ECOLI DNA replication terminus site-binding protein (Gene Name=tus)

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