Structure of PDB 2hvr Chain A

Receptor sequence
>2hvrA (length=319) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
SMFKKYSSLENHYNSKFIEKLYSLGLTGGEWVAREKIHGTNFSLIIERDK
VTCAKRTGPILPAEDFFGYEIILKNYADSIKAVQDIMETSAVVSYQVFGE
FAGPGIQKNVDYGDKDFYVFDIIVTTESGDVTYVDDYMMESFCNTFKFKM
APLLGRGKFEELIKLPNDLDSVVQDYNFTVDHAGLVDANKCVWNAEAKGE
VFTAEGYVLKPCYPSWLRNGNRVAIKCKNSKFELSEADNKLVGILACYVT
LNRVNNVISKIGEIGPKDFGKVMGLTVQDILEETSREGITLTQADNPSLI
KKELVKMVQDVLRPAWIEL
3D structure
PDB2hvr RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.5.1.3: RNA ligase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A F66 G104 F67 G105
BS02 dna A T39 N40 K54 R55 T56 Q106 T40 N41 K55 R56 T57 Q107
BS03 dna A Y5 K35 I36 N40 R55 E99 F119 V207 K225 K227 Y6 K36 I37 N41 R56 E100 F120 V208 K226 K228
Gene Ontology
Molecular Function
GO:0003972 RNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0042245 RNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2hvr, PDBe:2hvr, PDBj:2hvr
PDBsum2hvr
PubMed17018278
UniProtP32277|RLIG2_BPT4 RNA ligase 2 (Gene Name=Y10A)

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