Structure of PDB 2hup Chain A

Receptor sequence
>2hupA (length=162) Species: 9606 (Homo sapiens) [Search protein sequence]
YDFLFKLVLVGDASVGKTCVVQRFKTGAFDFTMKTLEIQGKRVKLQIWDT
AGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNI
VQLLIGNKSDLSELREVSLAEAQSLAEHYDILCAIETSAKDSSNVEEAFL
RVATELIMRHGG
3D structure
PDB2hup Crystal structure of human RAB43 in complex with GDP
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) V35 Q77
Catalytic site (residue number reindexed from 1) V21 Q53
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A S28 V29 G30 K31 T32 C33 F43 N131 K132 D134 L135 S162 A163 K164 S14 V15 G16 K17 T18 C19 F29 N107 K108 D110 L111 S138 A139 K140
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2hup, PDBe:2hup, PDBj:2hup
PDBsum2hup
PubMed
UniProtQ86YS6|RAB43_HUMAN Ras-related protein Rab-43 (Gene Name=RAB43)

[Back to BioLiP]