Structure of PDB 2hs3 Chain A

Receptor sequence
>2hs3A (length=602) Species: 2336 (Thermotoga maritima) [Search protein sequence]
KLRYLNILKEKLGREPTFVELQAFSVMWSEHCGYSHTKKYIRRLPKTGFE
GNAGVVNLDDYYSVAFKIESHNHPSAIEPYNGAATGVGGIIRDVLAMGAR
PTAIFDSLHMSRIIDGIIEGIADYGNSIGVPTVGGELRISSLYAHNPLVN
VLAAGVVRNDMLVDSKASRPGQVIVIFGGATGRDGIHGASFASEDLTGDK
ATKLSIQVGDPFAEKMLIEAFLEMVEEGLVEGAQDLGAGGVLSATSELVA
KGNLGAIVHLDRVPLREPDMEPWEILISESQERMAVVTSPQKASRILEIA
RKHLLFGDVVAEVIEEPVYRVMYRNDLVMEVPVQLLANAPEEDIVEYTPG
KIPEFKRVEFEEVNAREVFEQYDHMVGTDTVVPPGFGAAVMRIKRDGGYS
LVTHSRADLALQDTYWGTLIAVLESVRKTLSVGAEPLAITNCVNYGDPDV
DPVGLSAMMTALKNACEFSGVPVASGNASLYNTYQGKPIPPTLVVGMLGK
VNPQKVAKPKPSKVFAVGWNDFELEREKELWRAIRKLSEEGAFILSSSQL
LTRTHVETFREYGLKIEVKLPEVRPAHQMVLVFSERTPVVDVPVKEIGTL
SR
3D structure
PDB2hs3 Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.5.3: phosphoribosylformylglycinamidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FGR A H32 S71 H72 N73 H74 P75 G90 R93 G189 A190 A193 Q208 A239 E280 Q282 S480 H31 S70 H71 N72 H73 P74 G89 R92 G188 A189 A192 Q207 A238 E279 Q281 S479
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004642 phosphoribosylformylglycinamidine synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2hs3, PDBe:2hs3, PDBj:2hs3
PDBsum2hs3
PubMed17154526
UniProtQ9X0X3|PURL_THEMA Phosphoribosylformylglycinamidine synthase subunit PurL (Gene Name=purL)

[Back to BioLiP]