Structure of PDB 2hrl Chain A

Receptor sequence
>2hrlA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
DYSLTMQSSVTVQEGMCVHVRCSFSYPVDSDPVHGYWFRAGNDISWKAPV
ATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKG
NIKWNYKYDQLSVNVT
3D structure
PDB2hrl Siglec-7 Undergoes a Major Conformational Change When Complexed with the {alpha}(2,8)-Disialylganglioside GT1b
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A W74 R124 W46 R96
BS02 SIA A R124 K131 W132 N133 K135 R96 K103 W104 N105 K107
BS03 CEQ A Y64 W74 R124 Y36 W46 R96
External links
PDB RCSB:2hrl, PDBe:2hrl, PDBj:2hrl
PDBsum2hrl
PubMed16895906
UniProtQ9Y286|SIGL7_HUMAN Sialic acid-binding Ig-like lectin 7 (Gene Name=SIGLEC7)

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