Structure of PDB 2hf3 Chain A

Receptor sequence
>2hf3A (length=364) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
DEEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRKDSYVGDEAQSK
RGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLN
PKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSH
TVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTEEREIVRD
IKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNERFRCPEAL
FQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMYPGIAD
RMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQE
YDESGPSIVHRKCF
3D structure
PDB2hf3 Crystal Structures of Expressed Non-polymerizable Monomeric Actin in the ADP and ATP States.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Q263 S265 Q252 S254
BS02 ADP A S14 G15 K18 G156 D157 G182 K213 E214 G301 G302 M305 Y306 S13 G14 K17 G145 D146 G171 K202 E203 G290 G291 M294 Y295
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hf3, PDBe:2hf3, PDBj:2hf3
PDBsum2hf3
PubMed16920713
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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