Structure of PDB 2hei Chain A

Receptor sequence
>2heiA (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
ICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLTVK
FEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQR
QASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNV
NDLFLAIAKKLPK
3D structure
PDB2hei Crystal structure of human RAB5B in complex with GDP
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GDP A A30 V31 G32 K33 S34 S35 F45 E47 Y48 S51 N133 K134 D136 L137 S163 A164 K165 A13 V14 G15 K16 S17 S18 F28 E30 Y31 S34 N113 K114 D116 L117 S143 A144 K145
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2hei, PDBe:2hei, PDBj:2hei
PDBsum2hei
PubMed
UniProtP61020|RAB5B_HUMAN Ras-related protein Rab-5B (Gene Name=RAB5B)

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