Structure of PDB 2heh Chain A

Receptor sequence
>2hehA (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
NWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEI
DVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFT
ARPLVQTIFEGGKATCFAYGQTGSGKTHTMGKGIYAMASRDVFLLKNQPC
YRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLV
NSADDVIKMIDMGSACRNSSRSHACFQIILRAKGRMHGKFSLVDLAGNEG
AEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIA
TISPGISSCEYTLNTLRYADRVKE
3D structure
PDB2heh Crystal structure of the kif2c motor domain
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A R266 P267 T350 G351 G353 K354 T355 H356 R38 P39 T122 G123 G125 K126 T127 H128
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function

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Biological Process
External links
PDB RCSB:2heh, PDBe:2heh, PDBj:2heh
PDBsum2heh
PubMed
UniProtQ99661|KIF2C_HUMAN Kinesin-like protein KIF2C (Gene Name=KIF2C)

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