Structure of PDB 2hb5 Chain A

Receptor sequence
>2hb5A (length=150) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]
HGTRPDLTDQPLPDADHTWYTDGSSLLQEGQRKAGAAVTTETEVIWAKAL
PAGTSAQRAELIALTQALKMAEGKKLNVYTDSRYAFATAHLTSEGKEIKN
KDEILALLKALFLPKRLSIIHCGHSAEARGNRMADQAARKAAITETPDTS
3D structure
PDB2hb5 Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D28 E66 D87 D22 E60 D81
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:2hb5, PDBe:2hb5, PDBj:2hb5
PDBsum2hb5
PubMed16912289
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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