Structure of PDB 2h8g Chain A

Receptor sequence
>2h8gA (length=246) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
ILRPISSVVFVIAMQAEALPLVNKFGLSETTDSPLGKGLPWVLYHGVHKD
LRINVVCPGRDAALGIDSVGTVPASLITFASIQALKPDIIINAGTCGGFK
VKGANIGDVFLVSDVVFHDRRIPIPMFDLYGVGLRQAFSTPNLLKELNLK
IGRLSTGDSLDMSTQDETLIIANDATLKDMEGAAVAYVADLLKIPVVFLK
AVTDLVDGDKPTAEEFLQNLTVVTAALEGTATKVINFINGRNLSDL
3D structure
PDB2h8g Crystal structure of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana at 1.5-A resolution
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.16: methylthioadenosine nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A C117 G118 L181 K199 D200 M201 D225 F237 C96 G97 L160 K178 D179 M180 D204 F216
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008930 methylthioadenosine nucleosidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0009086 methionine biosynthetic process
GO:0009116 nucleoside metabolic process
GO:0010087 phloem or xylem histogenesis
GO:0019509 L-methionine salvage from methylthioadenosine
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:2h8g, PDBe:2h8g, PDBj:2h8g
PDBsum2h8g
PubMed16909418
UniProtQ9T0I8|MTN1_ARATH 5'-methylthioadenosine nucleosidase (Gene Name=MTN1)

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