Structure of PDB 2h6p Chain A

Receptor sequence
>2h6pA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB2h6p Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 R62 N63 I66 T69 T73 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 Q155 Y159 W167 Y171 Y7 R62 N63 I66 T69 T73 S77 Y84 R97 Y99 S116 T143 K146 W147 A150 Q155 Y159 W167 Y171
External links
PDB RCSB:2h6p, PDBe:2h6p, PDBj:2h6p
PDBsum2h6p
PubMed16963442
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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