Structure of PDB 2h3c Chain A

Receptor sequence
>2h3cA (length=72) Species: 562 (Escherichia coli) [Search protein sequence]
MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERWKVENQE
GMVEVARFIEMNGSFADENKDW
3D structure
PDB2h3c Structural Basis for Nucleic Acid and Toxin Recognition of the Bacterial Antitoxin CcdA
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R4 T6 R4 T6 PDBbind-CN: Kd=88.5uM
BS02 dna A K2 R4 Y14 N23 S25 K2 R4 Y14 N23 S25 PDBbind-CN: Kd=88.5uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0097351 toxin sequestering activity
Biological Process
GO:0032984 protein-containing complex disassembly
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0017053 transcription repressor complex
GO:0110001 toxin-antitoxin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:2h3c, PDBe:2h3c, PDBj:2h3c
PDBsum2h3c
PubMed17007877
UniProtP62552|CCDA_ECOLI Antitoxin CcdA (Gene Name=ccdA)

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