Structure of PDB 2gww Chain A

Receptor sequence
>2gwwA (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
HMPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQA
AVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDP
YSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAE
VVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVK
ELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQ
LTSWDEDAW
3D structure
PDB2gww Shigella applies molecular mimicry to subvert vinculin and invade host cells.
ChainA
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I12 V16 Q19 P43 A46 V47 A50 V57 T61 S112 F126 I13 V17 Q20 P44 A47 V48 A51 V58 T62 S113 F127
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005198 structural molecule activity
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0015629 actin cytoskeleton

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gww, PDBe:2gww, PDBj:2gww
PDBsum2gww
PubMed17088427
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

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