Structure of PDB 2gui Chain A

Receptor sequence
>2guiA (length=176) Species: 562 (Escherichia coli) [Search protein sequence]
ITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKP
DRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDI
GFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEI
DNSKRTLHGALLDAQILAEVYLAMTG
3D structure
PDB2gui Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D12 E14 E61 H162 D167
Catalytic site (residue number reindexed from 1) D8 E10 E57 H158 D163
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D12 E14 G163 D167 D8 E10 G159 D163
BS02 U5P A D12 E14 T15 G17 M18 E61 A62 V65 F102 H162 D8 E10 T11 G13 M14 E57 A58 V61 F98 H158
BS03 U5P A H98 N99 S144 L145 R159 H94 N95 S140 L141 R155
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2gui, PDBe:2gui, PDBj:2gui
PDBsum2gui
PubMed
UniProtP03007|DPO3E_ECOLI DNA polymerase III subunit epsilon (Gene Name=dnaQ)

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