Structure of PDB 2gry Chain A

Receptor sequence
>2gryA (length=327) Species: 9606 (Homo sapiens) [Search protein sequence]
EIMCMIRDFRGSLDYRPLPIDEHRICVCVRKRPLNKKETQMKDLDVITIP
SKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVE
TIFERGMATCFAYGQTGSGKTHTMGGSKGIYALAARDVFLMLKKPNYKKL
ELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVE
DVLKLIDIGNSCRTHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERDRQ
TRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSR
TCMIATISPGMASCENTLNTLRYANRV
3D structure
PDB2gry Crystal structure of the human KIF2 motor domain in complex with ADP
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A R204 P205 T288 G289 G291 K292 T293 H294 R32 P33 T116 G117 G119 K120 T121 H122
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function

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Biological Process
External links
PDB RCSB:2gry, PDBe:2gry, PDBj:2gry
PDBsum2gry
PubMed
UniProtO00139|KIF2A_HUMAN Kinesin-like protein KIF2A (Gene Name=KIF2A)

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