Structure of PDB 2gmk Chain A

Receptor sequence
>2gmkA (length=104) Species: 8404 (Lithobates pipiens) [Search protein sequence]
QDWLTFQKKHITNTRDVDCDNIMSTNLFHCKDKNTFIYSRPEPVKAICKG
IIASKNVLTTSEFYLSDCNVTSRPCKYKLKKSTNKFCVNCANQAPVHFVG
VGSC
3D structure
PDB2gmk Structural basis for catalysis by onconase.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.27.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A K9 K31 K9 K31 MOAD: Ki=590uM
PDBbind-CN: -logKd/Ki=3.23,Ki=590uM
BS02 AMP A K9 H10 H97 F98 K9 H10 H97 F98 MOAD: Ki=590uM
PDBbind-CN: -logKd/Ki=3.23,Ki=590uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004540 RNA nuclease activity
Biological Process
GO:0050830 defense response to Gram-positive bacterium

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Molecular Function
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Biological Process
External links
PDB RCSB:2gmk, PDBe:2gmk, PDBj:2gmk
PDBsum2gmk
PubMed18001769
UniProtP22069|RNP30_LITPI Protein P-30

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