Structure of PDB 2gjw Chain A

Receptor sequence
>2gjwA (length=308) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
HHHHIGGDFAVVKAKKSLERRGFGVKRGDKIYLHPLEVVYLQIKGIESFG
ELEDVLSWAESRMEDFSTYYFVYEDLRDRGNKVKIQGEFLLTKKPYLPIS
ERKTIRMEEIAEKARNFDELRLAVVDEESEITYFRVYEPDMMGEQKEELP
EIAGVLSDEYVITKQTEIFSRYFYGSEKGDLVTLSLIESLYLLDLGKLNL
LNADREELVKRAREVERNFDRRYEVYRNLKERGFVVKTGFKFGSEFRVYR
KVESVDDLPHSEYLVDIADSREIRLIDLARAVRLAQNVRKRMVFAYGKNY
LCFERVKV
3D structure
PDB2gjw RNA Recognition and Cleavage by an Splicing Endonuclease
ChainA
Resolution2.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y249 H260 K290
Catalytic site (residue number reindexed from 1) Y249 H260 K290
Enzyme Commision number 4.6.1.16: tRNA-intron lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F173 F242 R247 Y249 L258 H260 S261 V288 K290 F173 F242 R247 Y249 L258 H260 S261 V288 K290
BS02 rna A R283 N287 R289 R305 R283 N287 R289 R305
Gene Ontology
Molecular Function
GO:0000213 tRNA-intron endonuclease activity
GO:0003676 nucleic acid binding
GO:0016829 lyase activity
Biological Process
GO:0000379 tRNA-type intron splice site recognition and cleavage
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0008033 tRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2gjw, PDBe:2gjw, PDBj:2gjw
PDBsum2gjw
PubMed16690865
UniProtO29362|ENDA_ARCFU tRNA-splicing endonuclease (Gene Name=endA)

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