Structure of PDB 2ghq Chain A

Receptor sequence
>2ghqA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
QYLLPEAKAQDSDKICVVINLDETLVHSSFKPVNNADFIIPVEIDGVVHQ
VYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARL
FRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWF
DNMSDTELHDLLPFFEQLSRVDDVYSVLRQ
3D structure
PDB2ghq Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N96 L97 D98 T152 A153 S154 L155 Y158 R178 Y188 N20 L21 D22 T76 A77 S78 L79 Y82 R102 Y112
BS02 MG A N96 D98 N207 N20 D22 N131
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:2ghq, PDBe:2ghq, PDBj:2ghq
PDBsum2ghq
PubMed17157258
UniProtQ9GZU7|CTDS1_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Gene Name=CTDSP1)

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