Structure of PDB 2ggx Chain A

Receptor sequence
>2ggxA (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
ASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPF
TEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKF
TYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCE
F
3D structure
PDB2ggx Contributions of Phenylalanine 335 to Ligand Recognition by Human Surfactant Protein D: ring interactions with Sp-D ligands
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E321 N323 E329 N341 D342 E117 N119 E125 N137 D138
BS02 CA A D297 E301 D324 E329 D330 D93 E97 D120 E125 D126
BS03 CA A E301 D330 E97 D126
BS04 NPJ A E321 N323 E329 F335 T336 N337 N341 R343 E117 N119 E125 F131 T132 N133 N137 R139 MOAD: ic50=0.32mM
PDBbind-CN: -logKd/Ki=3.49,IC50=0.32mM
External links
PDB RCSB:2ggx, PDBe:2ggx, PDBj:2ggx
PDBsum2ggx
PubMed16636058
UniProtP35247|SFTPD_HUMAN Pulmonary surfactant-associated protein D (Gene Name=SFTPD)

[Back to BioLiP]