Structure of PDB 2get Chain A

Receptor sequence
>2getA (length=308) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
SEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYL
PLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKS
TTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYN
RRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLN
VLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADPESHF
HHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSI
NRLRLRKL
3D structure
PDB2get Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.33: pantothenate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COK A G39 V99 A100 K103 R108 H179 Y235 R238 F239 M242 F254 I272 N277 G35 V95 A96 K99 R104 H175 Y231 R234 F235 M238 F250 I268 N273
Gene Ontology
Molecular Function
GO:0004594 pantothenate kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2get, PDBe:2get, PDBj:2get
PDBsum2get
PubMed16699190
UniProtP9WPA7|COAA_MYCTU Pantothenate kinase (Gene Name=coaA)

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