Structure of PDB 2geq Chain A

Receptor sequence
>2geqA (length=188) Species: 10090 (Mus musculus) [Search protein sequence]
QKTYQGNYGFHLGFLQSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAG
SRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPE
YLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTI
ITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKK
3D structure
PDB2geq Structure of the p53 Core Domain Dimer Bound to DNA.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S238 R270 A273 R277 S137 R169 A172 R176
BS02 ZN A C173 H176 C235 C239 C72 H75 C134 C138
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2geq, PDBe:2geq, PDBj:2geq
PDBsum2geq
PubMed16717092
UniProtP02340|P53_MOUSE Cellular tumor antigen p53 (Gene Name=Tp53)

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