Structure of PDB 2gc1 Chain A

Receptor sequence
>2gc1A (length=188) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MMYKEPFGVKVDFETGIIEGAKKSVRRLSDMEGYFVDERAWKELVEKEDP
VVYEVYAVEQEEKEGDLNFATTVLYPGKVGKEFFFTKGHFHAKLDRAEVY
VALKGKGGMLLQTPEGDAKWISMEPGTVVYVPPYWAHRTVNIGDEPFIFL
AIYPADAGHDYGTIAEKGFSKIVIEENGEVKVVDNPRW
3D structure
PDB2gc1 Evidence Supporting a cis-enediol-based Mechanism for Pyrococcus furiosus Phosphoglucose Isomerase
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.1.9: glucose-6-phosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 S6P A Y52 T71 T85 G87 H88 E97 Y99 H136 Y160 Y53 T72 T86 G88 H89 E98 Y100 H137 Y161
BS02 ZN A H88 H90 E97 H136 H89 H91 E98 H137
BS03 ZN A D143 E144 D144 E145
Gene Ontology
Molecular Function
GO:0004347 glucose-6-phosphate isomerase activity
GO:0005506 iron ion binding
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
GO:0006096 glycolytic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2gc1, PDBe:2gc1, PDBj:2gc1
PDBsum2gc1
PubMed16580686
UniProtP83194|G6PI_PYRFU Glucose-6-phosphate isomerase (Gene Name=pgiA)

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