Structure of PDB 2g8w Chain A

Receptor sequence
>2g8wA (length=134) Species: 86665 (Halalkalibacterium halodurans) [Search protein sequence]
KEEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGE
FLAIVHGLRYLKERNSRKPIYSDSQTAIKWVKDKKAKSTLVRNEETALIW
KLVDEAEEWLNTHTYETPILKWQTDKWGAIKADY
3D structure
PDB2g8w Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A D132 S133 Q134 K180 D73 S74 Q75 K121
BS02 dna A N77 T104 N105 N106 K138 W139 K146 S147 T148 N18 T45 N46 N47 K79 W80 K87 S88 T89
BS03 CA A D71 E109 D132 D12 E50 D73
BS04 CA A D71 D192 D12 D133
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:2g8w, PDBe:2g8w, PDBj:2g8w
PDBsum2g8w
PubMed16601679
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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