Structure of PDB 2g8i Chain A

Receptor sequence
>2g8iA (length=134) Species: 86665 (Halalkalibacterium halodurans) [Search protein sequence]
EIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEFL
AIVHGLRYLKERNSRKPIYSDSQTAIKWVKDKKAKSTLVRNEETALIWKL
VDEAEEWLNTHTYETPILKWQTDKWGEIKANYGR
3D structure
PDB2g8i Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release.
ChainA
Resolution1.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A N105 E109 D132 Q134 K180 T183 N44 E48 D71 Q73 K119 T122
BS02 dna A N77 P78 T104 N105 N106 Q134 K138 W139 S147 T148 N16 P17 T43 N44 N45 Q73 K77 W78 S86 T87
BS03 MN A D71 E109 D132 D10 E48 D71
BS04 MN A D71 N192 D10 N131
BS05 MN A D163 E166 D102 E105
BS06 MN A E82 E96 E21 E35
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:2g8i, PDBe:2g8i, PDBj:2g8i
PDBsum2g8i
PubMed16601679
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

[Back to BioLiP]