Structure of PDB 2g5r Chain A

Receptor sequence
>2g5rA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
KDYSLTMQSSVTVQEGMCVHVRCSFSYPSQTDSDPVHGYWFRAGKAPVAT
NNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNI
KWNYKYDQLSVNVT
3D structure
PDB2g5r The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NXD A R124 K131 W132 N133 K135 R94 K101 W102 N103 K105
BS02 CYS A C41 V42 H43 C18 V19 H20
External links
PDB RCSB:2g5r, PDBe:2g5r, PDBj:2g5r
PDBsum2g5r
PubMed16623661
UniProtQ9Y286|SIGL7_HUMAN Sialic acid-binding Ig-like lectin 7 (Gene Name=SIGLEC7)

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