Structure of PDB 2g4b Chain A

Receptor sequence
>2g4bA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
LGSARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQD
KNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGAHKLFIG
GLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTD
QAIAGLNGMQLGDKKLLVQRAS
3D structure
PDB2g4b Structural basis of polypyrimidine tract recognition by the essential splicing factor U2AF65.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R150 Y152 K195 N196 F199 K225 R227 P229 H230 D231 R6 Y8 K51 N52 F55 K81 R83 P85 H86 D87 PDBbind-CN: Kd=1.8uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:2g4b, PDBe:2g4b, PDBj:2g4b
PDBsum2g4b
PubMed16818232
UniProtP26368|U2AF2_HUMAN Splicing factor U2AF 65 kDa subunit (Gene Name=U2AF2)

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