Structure of PDB 2g3h Chain A

Receptor sequence
>2g3hA (length=153) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MNSDEVQLIKKTWEIPVATPTDSGAAILTQFFNRFPSNLEKFPFRDVPLE
ELSGNARFRAHAGRIIRVFDESIQVLGQDGDLEKLDEIWTKIAVSHIPRT
VSKESYNQLKGVILDVLTAASSLDESQAATWAKLVDHVYGIIFKAIDDDG
NAK
3D structure
PDB2g3h Cyanide binding and heme cavity conformational transitions in Drosophila melanogaster hexacoordinate hemoglobin.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.1.7: peroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A N38 K41 F42 P43 R57 H61 I65 W89 S95 H96 R99 V101 Y106 L109 N38 K41 F42 P43 R57 H61 I65 W89 S95 H96 R99 V101 Y106 L109
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0005344 oxygen carrier activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0140825 lactoperoxidase activity
Biological Process
GO:0001666 response to hypoxia
GO:0015671 oxygen transport
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:2g3h, PDBe:2g3h, PDBj:2g3h
PDBsum2g3h
PubMed16906763
UniProtQ9VF15

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