Structure of PDB 2g30 Chain A

Receptor sequence
>2g30A (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
GGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFA
IQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQ
VAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQI
KECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELR
IQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN
3D structure
PDB2g30 Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R834 Q835 L838 W841 E849 A877 R879 V881 E882 Y888 E902 S915 R130 Q131 L134 W137 E145 A173 R175 V177 E178 Y184 E198 S211
BS02 peptide A Q756 N758 Y815 Q52 N54 Y111
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2g30, PDBe:2g30, PDBj:2g30
PDBsum2g30
PubMed16516836
UniProtP63010|AP2B1_HUMAN AP-2 complex subunit beta (Gene Name=AP2B1)

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