Structure of PDB 2g2z Chain A

Receptor sequence
>2g2zA (length=307) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
QFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDLWALTQQGP
AEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAE
GQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHC
ALMKPAADKLAVELAKITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLY
NPVQWTKSVEYMAAQGVEHLYEVGPGKVLTGLTKRIVDTLTASALNEPSA
MAAALEL
3D structure
PDB2g2z Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q11 S92 L93 R117 H201 Q250
Catalytic site (residue number reindexed from 1) Q9 S90 L91 R115 H199 Q248
Enzyme Commision number 2.3.1.39: [acyl-carrier-protein] S-malonyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COZ A Q11 I136 N160 P164 G165 Q166 R190 V280 R287 Q9 I134 N158 P162 G163 Q164 R188 V278 R285
Gene Ontology
Molecular Function
GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2g2z, PDBe:2g2z, PDBj:2g2z
PDBsum2g2z
PubMed16699188
UniProtP0AAI9|FABD_ECOLI Malonyl CoA-acyl carrier protein transacylase (Gene Name=fabD)

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