Structure of PDB 2g1p Chain A

Receptor sequence
>2g1pA (length=244) Species: 562 (Escherichia coli) [Search protein sequence]
KNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYIL
ADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFA
EKAQNAFFYCESYADSMARADDSSVVYCDPPYAPLNSFTLEQQAHLAEIA
EGLVERHIPVLISNHDTMLTREWYQRAKLHVVKKVDELLALYKP
3D structure
PDB2g1p Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase.
ChainA
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K9 A11 G12 R116 N120 Y138 Y184 H228 V261 K7 A9 G10 R114 N118 Y136 Y182 H215 V235
BS02 dna A R95 Y119 R124 N126 L127 N132 P134 R137 R93 Y117 R122 N124 L125 N130 P132 R135
BS03 SAH A W10 K14 P34 F35 A38 D54 I55 S164 Y165 D181 W8 K12 P32 F33 A36 D52 I53 S162 Y163 D179
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
GO:0043565 sequence-specific DNA binding
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006298 mismatch repair
GO:0009307 DNA restriction-modification system
GO:0009411 response to UV
GO:0032259 methylation
GO:1902328 bacterial-type DNA replication initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:2g1p, PDBe:2g1p, PDBj:2g1p
PDBsum2g1p
PubMed16524590
UniProtP0AEE8|DMA_ECOLI DNA adenine methylase (Gene Name=dam)

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