Structure of PDB 2fvs Chain A

Receptor sequence

>2fvsA (length=255) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]

TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVE
DIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWR
DPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYV
DDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLL
KEGQR

3D structure

PDB

2fvs Crystal structures of oligonucleotides including the integrase processing site of the Moloney murine leukemia virus.

Chain

Resolution

2.35 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y64 L99 R116	Y41 L76 R93

External links

PDB	RCSB:2fvs, PDBe:2fvs, PDBj:2fvs
PDBsum	2fvs
PubMed	17003051
UniProt	P03355\|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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