Structure of PDB 2fsa Chain A

Receptor sequence
>2fsaA (length=168) Species: 9606 (Homo sapiens) [Search protein sequence]
DTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQ
CQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDY
YGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFY
QCAEVLESFFVQKLKGFK
3D structure
PDB2fsa Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y10 Y17 E19 F22 Y23 I24 G25 C26 D27 W32 I48 D49 Y5 Y12 E14 F17 Y18 I19 G20 C21 D22 W27 I43 D44
BS02 ZN A C11 C13 H34 C37 C6 C8 H29 C32
BS03 ZN A C26 C29 C53 C56 C21 C24 C48 C51
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:2fsa, PDBe:2fsa, PDBj:2fsa
PDBsum2fsa
PubMed16728978
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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