Structure of PDB 2fr4 Chain A

Receptor sequence

>2fr4A (length=213) Species: 10090 (Mus musculus) [Search protein sequence]

ELQMTQSPASLSASVGETVTITCRASENIYSYLAWYQQKQGKSPQLLVYN
AKTLAEGVPSRFSGSGSGTQFSLKINSLQPEDFGSYYCQHHYGTPLTFGA
GTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKI
DGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRNE

3D structure

PDB

2fr4 Impact of DNA hairpin folding energetics on antibody-ssDNA association.

Chain

Resolution

1.95 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y32 Y49 N50 H91	Y32 Y49 N50 H91	PDBbind-CN: Kd=4uM

External links

PDB	RCSB:2fr4, PDBe:2fr4, PDBj:2fr4
PDBsum	2fr4
PubMed	18028946

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