Structure of PDB 2fqx Chain A

Receptor sequence
>2fqxA (length=316) Species: 160 (Treponema pallidum) [Search protein sequence]
GDFVVGMVTDSGDIDDKSFNQQVWEGISRFAQENNAKCKYVTASTDAEYV
PSLSAFADENMGLVVACGSFLVEAVIETSARFPKQKFLVIDAVVQDRDNV
VSAVFGQNEGSFLVGVAAALKAKEAGKSAVGFIVGMELGMMPLFEAGFEA
GVKAVDPDIQVVVEVANTFSDPQKGQALAAKLYDSGVNVIFQVAGGTGNG
VIKEARDRRLNGQDVWVIGVDRDQYMDGVYDGSKSVVLTSMVKRADVAAE
RISKMAYDGSFPGGQSIMFGLEDKAVGIPEENPNLSSAVMEKIRSFEEKI
VSKEIVVPVRSARMMN
3D structure
PDB2fqx The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GMP A D27 F36 N37 D108 M158 F186 V210 G212 V237 D238 K260 D10 F19 N20 D91 M141 F169 V193 G195 V220 D221 K243 MOAD: Kd=71nM
PDBbind-CN: -logKd/Ki=7.15,Kd=71nM
Gene Ontology
Cellular Component
GO:0005886 plasma membrane

View graph for
Cellular Component
External links
PDB RCSB:2fqx, PDBe:2fqx, PDBj:2fqx
PDBsum2fqx
PubMed16418175
UniProtP29724|TMPC_TREPA Membrane lipoprotein TmpC (Gene Name=tmpC)

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