Structure of PDB 2fpu Chain A

Receptor sequence
>2fpuA (length=158) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence]
SQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPQLLKLQKAGYKLV
MITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADEC
DCRKPKVKLVERYLMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNW
PMIGEQLT
3D structure
PDB2fpu Structural snapshots of Escherichia coli histidinol phosphate phosphatase along the reaction pathway.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.15: histidinol-phosphatase.
4.2.1.19: imidazoleglycerol-phosphate dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C94 H96 C102 C104 C92 H94 C100 C102
BS02 MG A D10 D12 D131 D8 D10 D125
Gene Ontology
Molecular Function
GO:0004401 histidinol-phosphatase activity
GO:0004424 imidazoleglycerol-phosphate dehydratase activity
GO:0016791 phosphatase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2fpu, PDBe:2fpu, PDBj:2fpu
PDBsum2fpu
PubMed16966333
UniProtQ9S5G5|HIS7_ECO57 Histidine biosynthesis bifunctional protein HisB (Gene Name=hisB)

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