Structure of PDB 2for Chain A

Receptor sequence
>2forA (length=283) Species: 623 (Shigella flexneri) [Search protein sequence]
DFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPFL
VYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTC
HVKFGEANAILAGDALQTLAFSILSDANMPEVSDRDRISMISELASASGI
AGMCGGQALDLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKG
RRALPVLDKYAESIGLAFQVQDDILDVVGGKSTYPALLGLEQARKKARDL
IDDARQALKQLAEQSLDTSALEALADYIIQRNK
3D structure
PDB2for Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IPR A K45 L47 R48 D223 R297 K44 L46 R47 D222 R281
Gene Ontology
Molecular Function
GO:0004337 geranyltranstransferase activity
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0045337 farnesyl diphosphate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2for, PDBe:2for, PDBj:2for
PDBsum2for
PubMed
UniProtA0A0H2UXE9

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