Structure of PDB 2fk2 Chain A

Receptor sequence
>2fk2A (length=59) Species: 9606 (Homo sapiens) [Search protein sequence]
EACKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
GVEFVCCPL
3D structure
PDB2fk2 Structural Studies of the Alzheimer's Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions
ChainA
Resolution1.65 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CU1 A H147 H151 Y168 H17 H21 Y38
Gene Ontology
Molecular Function
GO:0046914 transition metal ion binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:2fk2, PDBe:2fk2, PDBj:2fk2
PDBsum2fk2
PubMed17239395
UniProtP05067|A4_HUMAN Amyloid-beta precursor protein (Gene Name=APP)

[Back to BioLiP]